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影响因子：16.4
DOI码：10.1002/anie.201908451
发表刊物：Angewandte Chemie International Edition
摘要：The synthesis of carboxylic acids is of fundamental importance in the chemical industry and the corresponding products find numerous applications for polymers, cosmetics, pharmaceuticals, agrochemicals, and other manufactured chemicals. Although hydroxycarbonylations of olefins have been known for more than 60 years, currently known catalyst systems for this transformation do not fulfill industrial requirements, for example, stability. Presented herein for the first time is an aqueous-phase protocol that allows conversion of various olefins, including sterically hindered and demanding tetra-, tri-, and 1,1-disubstituted systems, as well as terminal alkenes, into the corresponding carboxylic acids in excellent yields. The outstanding stability of the catalyst system (26 recycling runs in 32 days without measurable loss of activity), is showcased in the preparation of an industrially relevant fatty acid. Key-to-success is the use of a built-in-base ligand under acidic aqueous conditions. This catalytic system is expected to provide a basis for new cost-competitive processes for the industrial production of carboxylic acids.
合写作者：Duehren, Ricarda；Razzaq, Rauf；Dong, Kaiwu；Liu, Jie；Franke, Robert*；Jackstell, Ralf；Beller, Matthias*；
第一作者：Sang, Rui；Kucmierczyk, Peter
论文类型：期刊论文
通讯作者：Franke, Robert*；Beller, Matthias*；
文献类型：期刊
卷号：58
期号：40
页面范围：14365-14373
是否译文：否
发表时间：2019-10-01
收录刊物：SCI
发布期刊链接：https://onlinelibrary.wiley.com/doi/10.1002/anie.201908451