胡中韬，北京航空航天大学副教授、博士生导师，长期从事生物医学超声、智能成像与调控研究，聚焦跨颅超声原创突破与临床转化。围绕脑疾病无创治疗，构建了从声学理论、结构化波前调控、多模态影像引导与反馈成像到脑功能干预、血脑屏障开启与神经疾病治疗的完整创新链条。入选教育部海外引才计划、北京市高层次人才计划。主持国家重点研发计划课题、国家自然科学基金青年项目、广东省自然科学基金、国家重点实验室开放基金、北航敢为行动计划、前沿交叉基金等，作为骨干参与国家重大仪器专项、NIH R01等多项国家级与国际科研项目。在PNAS、Phys Rev Applied、Ultrasonics、Sci China Phys Mech、Nature Metabolism、JASA、IEEE-TUFFC、IEEE-TBME等期刊发表原创论文30余篇。授权/在审发明专利20余项（含中国16项、美国3项、PCT 1项、澳大利亚/加拿大/欧洲各1项），其中3项已成功转化，相关医疗仪器获 FDA突破性设备认证。研究成果被ScienceDaily、AAAS、PHYS.ORG、中国科学院官网等50余家媒体报道。多次受邀在国际学术会议及科研机构作大会特邀或主题报告，担任会议组委/分会场主席；担任Nature Communications、JASA、Ultrasonics、UMB、Ultrasonics Sonochemistry、声学学报、中国生物医学工程学报等期刊审稿人/客座编辑/编委。荣获戈登会议最佳学术报告奖、中国科学院院长奖、北航优秀导师等，任国家自然科学基金评审专家、国家公派博士项目评审专家、北京市科协专项行动特派员。指导学生获中国生物医学工程学会青年论文竞赛一等奖、中国生物医学工程创新设计竞赛二等奖、北京市大学生创新创业计划、研究生国家奖学金等。主讲《神经工程与脑机接口》等核心课程。
研究方向
1. 跨颅声波传播理论与仿真计算
研究声波在异质颅骨和脑组织中的传播机制，融合生物力学建模与高性能计算，构建面向个体的声场预测与校正框架，为精准聚焦提供理论基础。
2. 结构化声场调控与智能优化
发展基于艾里波、声学涡旋、编码超结构等结构化波前控制技术，结合人工智能算法进行调控参数优化与靶点匹配，实现深部脑区的高精度非侵入刺激。
3. 面向脑疾病的个体化无创干预系统
聚焦神经调控与血脑屏障开启等关键应用，开发集成多模态影像（MRI/CT/fMRI）与AI辅助决策的智能超声干预平台，推动帕金森病、抑郁症、脑卒中等脑疾病的精准治疗。
招生信息
欢迎具有生物医学工程、声学、力学、计算机科学与技术、电子科学与技术、机械工程、仪器科学与工程、基础医学等相关专业背景的本科生及研究生加入！课题组与国内外多家顶尖医学机构、实验室保持密切合作，提供国际联合培养、跨学科交叉研究与产业转化实践等多维度发展机会，打造科研与成长并重的学术平台。
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代表性期刊论文
Gao, H., Ding, S., Liu, Z., Zhang, J., Li, B., An, Z., Wang, L., Jing, J., Liu, T., Fan, Y. and Hu ZT.*, 2025. Rapid Simulation Framework Integrating MRI-Derived Synthetic CT for Precise Transcranial Focused Ultrasound Targeting, Science China-Physics Mechanics & Astronomy，https://www.sciengine.com/doi/10.1007/s11433-025-2777-1.
Linzhen Shu, Hua Shen, Yujie Zhou, Zixiao Li, Hu ZT.*, 2025, Harnessing the Power of Low-intensity Focused Ultrasound Stimulation in Stroke Modulating Immune Response, Stroke, https://www.ahajournals.org/doi/10.1161/STROKEAHA.125.052307
Zhang, Z., Ma, S., Yin, Z., Qiu, J., Hu ZT, Li, G.Y., Feng, X.Q. and Cao, Y., 2025. Unveiling hidden features of acoustic radiation forces in soft tissues via physics-informed neural network-based full shear wave inversion. Journal of the Mechanics and Physics of Solids, p.106326.
Ye, D., Chukwu, C., Yang, Y., Hu ZT., and Chen, H., 2024. Adeno-associated virus vector delivery to the brain: Technology advancements and clinical applications. Advanced Drug Delivery Reviews, p.115363.
Hu ZT., Yang, Y., Yang LQ, Gong Y, Chukwu C, Ye DZ et al. 2024. Airy-beam holographic sonogenetics for advancing neuromodulation precision and flexibility. PNAS, 121(26), p.e2402200121.
Zuo W., An Z., Zhang BX. and Hu ZT., 2024. Solution of nonlinear Lamb waves in plates with discontinuous thickness. The Journal of the Acoustical Society of America, (03):2171.
Yang Y., Yuan J., Field R., Ye D., Hu ZT., Gong Y., Xu K., Xu L., Yue Y., Kravitz A., Bruchas M., Cui J., Brestoff J. and Chen H., 2023. Induction of a torpor-like hypothermic and hypometabolic state in rodents by ultrasound. Nature Metabolism, 5(5), p. 789-803.
Hu ZT.*, Yang, Y., Ye, D., Chen, S., Gong, Y., Chukwu, C. and Chen, H., 2023. Targeted delivery of therapeutic agents to the mouse brain using a stereotactic-guided focused ultrasound device. STAR Protocols, 4(1), p.102132.
Ye D., Chen S., Liu Y., Weixel C., Hu ZT., Yuan J. and Chen H., 2023. Mechanically manipulating glymphatic transport by ultrasound combined with microbubbles. PNAS, 120(21), p.e2212933120.
Hu ZT., Chen, S., Yang, Y., Gong, Y. and Chen, H., 2022. An affordable and easy-to-use focused ultrasound device for noninvasive and high precision drug delivery to the mouse brain. IEEE Transactions on Biomedical Engineering, 69(9), p. 2723–2732.
Xu K., Yang Y., Hu ZT., Yue Y., Gong Y., Cui J., Culver J., Bruchas M. and Chen H., 2023. TRPV1-mediated sonogenetic neuromodulation of motor cortex in freely moving mice. Journal of Neural Engineering, 20(1), p.016055.
Hu ZT., Yang Y, Xu, L, Jing, Y. and Chen, H., 2022. Airy Beam-enabled Binary Acoustic Metasurfaces for Underwater Ultrasound Beam Manipulation. Physical Review Applied, 18(2), p. 024070.
Ye D., Yuan J., Yang Y., Yue Y., Hu ZT., Fadera Siaka, Chen H., 2022. Incisionless targeted adeno-associated viral vector delivery to the brain by focused ultrasound-mediated intranasal administration, EBioMedicine, 84, p.104277.
Hu ZT., Yang, YH., Xu, L., Hao, Y. and Chen, H., 2022. Binary acoustic metasurfaces for dynamic focusing of transcranial ultrasound. Frontiers in Neuroscience, p. 1473.
Xu L., Pacia C., Gong Y., Hu ZT., Chien CY., Yang LQ., Gach MH., Hao Y., Comron H., Huang JY., Leuthardt EC. and Chen H., 2022. Characterization of the Targeting Accuracy of a Neuronavigation-guided Transcranial FUS system in vitro, in vivo, and in silico, IEEE Transactions on Biomedical Engineering, 70(5), p. 1528–1538.
Hu ZT., Xu, L., Chien, C.Y., Yang, Y., Gong, Y., Ye, D., Pacia, C.P. and Chen, H., 2021. 3-D Transcranial Microbubble Cavitation Localization by Four Sensors. IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 68(11), p. 3336-3346.
Zuo W., Hu ZT., An Z. and Kong Y., 2020. LDV-based measurement of 2D dynamic stress fields in transparent solids. Journal of Sound and Vibration, 476, p.115288.
Hu ZT., An, Z., Kong, Y., Lian, G. and Wang, X., 2019. The nonlinear S0 Lamb mode in a plate with a linearly-varying thickness. Ultrasonics, 94, p. 102-108.
[Katsnelson B.G.*, Hu ZT.*], 2018. Sound Field in a Coastal Wedge in the Area of a Thermocline’s Contact with the Sea Bottom. Bulletin of the Russian Academy of Sciences: Physics, 82(5), p. 526-529.
Hu ZT., An, ZW., Lian, GX., and Wang, XM., 2017. Propagation properties of backward lamb waves in plate investigated by dynamic photoelastic technique. Chinese Physics Letters, 34(11), p. 114301.
An Z., Hu ZT., Mao J., Lian G. and Wang XM., 2017, December. Optical visualization of leaky Lamb wave and its application in nondestructive testing. The Journal of the Acoustical Society of America Vol. 32, No. 1, p. 030002.
近年代表性专利
一种基于漏兰姆波的探测固体板底部目标的装置及方法.CN110109124B. 中国发明专利. (1/7)
一种基于后退波的固体板厚度测量装置及其方法.CN109974639B.中国发明专利. (1/5)
基于漏兰姆波的感知固体板底部目标的装置及方法.CN110109122B. 中国发明专利. (1/6)
动态光弹性系统中超声应力与残余应力的分离方法.CN105651433B. 中国发明专利. (2/5)
一种光弹性实验中超声波应力定量测量方法.CN105571752B. 中国发明专利. (2/8)
基于动态光弹性系统的应力测量方法.CN105675186B. 中国发明专利. (2/9)
一种动态光弹超声成像方法和系统.CN107884061B. 中国发明专利. (2/7)
一种利用激光多普勒效应进行超声定量测量的方法和系统. CN109579971B. 中国发明专利. (3/7)
一种测量动态光弹图像中声传播方向的方法.CN110530499A. 中国发明专利. (2/6)
Three-dimensional Transcranial Microbubble Cavitation Localization, T-019601, US patent. (1/2)
Airy Beam-enabled Binary Acoustic Metasurfaces for Underwater Ultrasound Beam Manipulation, US20240019562A1, US patent (1/2)
Focused Ultrasound Device, US20230277831A1, US patent (2/5)
SYSTEMS AND METHODS FOR FOCUSED ULTRASOUND-ENABLED LIQUID BIOPSY. US20250040914A1, US patent (2/6)
Wearable sonocap for ultrasound-brain interfacing. US Patent Application No. 63/609,561, US patent (2/4)
Binary Acoustic Metasurfaces for Dynamic Focusing of Transcranial Ultrasound, T-020253, US patent. (1/2)
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