主要从事疾病状态下大脑皮层神经网络以及神经突触传递的机制研究，在运用在体双光子成像、电生理技术以及数学计算方法研究正常或疾病状态下（孤独症、脑卒中、阿尔茨海默症）神经网络动力学特性方面具有良好的学术背景与技术经验，目前共发表SCI论文10篇，其中第一或共同第一作者文章6篇，包括Protein & Cell, PNAS, Cell Reports, Bioinformatics,等。参与编写专著2部。主持国家自然科学基金青年基金、获北京大学博雅博后项目资助。参与多项国家级研究课题，包括国家重点研发计划（973），国家自然科学基金重点项目等。

研究方向：

1. 用电生理、双光子成像技术研究阿尔茨海默症和孤独症的致病机制。

2. 采用生物力学方法探索孤独症、阿尔茨海默病、脑卒中等神经疾病的康复策略。

相关发表文章：（*为共同一作，#为通讯作者）

1. Yang C*, Tian Y*, Su F*, Wang Y*, Liu M*, Wang H*, Cui Y*, Yuan P, Li X, Li A, Gong H, Luo Q, Zhu D, Cao P, Liu Y, Wang X, Luo MH, Xu F, Xiong W, Wang L, Li XY, Zhang C^#. Restoration of FMRP expression in adult V1 neurons rescues visual deficits in a mouse model of fragile X syndrome. Protein & Cell. 2022 Mar;13(3):203-219.

2. Tian Y*, Yang C*, Cui Y*, Su F*, Wang Y*, Wang Y*, Yuan P, Shang S, Li H, Zhao J, Zhu D, Tang S, Cao P, Liu Y, Wang X, Wang L, Zeng W, Jiang H, Zhao F, Luo M, Xiong W^#, Qiu Z^#, Li XY^#, Zhang C^#. An Excitatory Neural Assembly Encodes Short-Term Memory in the Prefrontal Cortex. Cell Rep. 2018 Feb 13;22(7):1734-1744.

3. Wei M*, Zhang J*, Jia M*, Yang C*, Pan Y, Li S, Luo Y, Zheng J, Ji J, Chen J, Hu X, Xiong J, Shi Y, Zhang C^#. α/β-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors. Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2695-704.

4. Yang H*, Yang C*, Zhu Q*, Wei M, Li Y, Cheng J, Liu F, Wu Y, Zhang J, Zhang C^#, Wu H^#. Rack1 Controls Parallel Fiber-Purkinje Cell Synaptogenesis and Synaptic Transmission. Front Cell Neurosci. 2019 Dec 17;13:539.

5. Tian Y*, Yang C*, Shang S*, Cai Y*, Deng X*, Zhang J, Shao F, Zhu D, Liu Y, Chen G, Liang J^#, Sun Q^#, Qiu Z^#, Zhang C^#. Loss of FMRP Impaired Hippocampal Long-Term Plasticity and Spatial Learning in Rats. Front Mol Neurosci. 2017 Aug 28;10:269.

6. Wang Y*, Su F*, Wang S*, Yang C*, Tian Y*, Yuan P*, Liu X, Xiong W, Zhang C^#. Efficient Implementation of Convolutional Neural Networks in the Data Processing of Two-Photon In Vivo Imaging. Bioinformatics. 2019 Sep 1;35(17):3208-3210.

7. Zhang H*, Kang E*, Wang Y*, Yang C, Yu H, Wang Q, Chen Z, Zhang C, Christian KM, Song H, Ming GL^#, Xu Z^#. Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice. Nat Commun. 2016 Jun 1;7:11773.

8. Ma J*, Qi X*, Yang C, Pan R, Wang S, Wu J, Huang L, Chen H, Cheng J, Wu, R, Liao Y, Mao L, Wang FC, Wu Z, An JX., Wang Y, Zhang X, Zhang C, and Yuan Z^#. Calhm2 governs astrocytic ATP releasing in the development of depression-like behaviors. Mol Psychiatry. 2018 Apr;23(4):1091.

9. Bao Z*, Fang K*, Miao Z*, Li C, Yang C, Yu Q, Zhang C, Miao Z, Liu Y^#, Ji J^#. Human Cerebral Organoid Implantation Alleviated the Neurological Deficits of Traumatic Brain Injury in Mice. Oxid Med Cell Longev. 2021 Nov 22;2021:6338722.

10. Liu Y, Shan L, Liu T, Li J, Chen Y, Sun C, Yang C, Bian X, Niu Y, Zhang C, Xi J, Rao Y^#. Molecular and cellular mechanisms of the first social relationship: A conserved role of 5-HT from mice to monkeys, upstream of oxytocin. Neuron. 2023 Feb 25:S0896-6273(23)00114-9.

11. Wang X*, Zheng W*, Zhu Z*, Xing B*, Yan W*, Zhu K, Xiao L, Yang C, Wei M, Yang L, Jin Z^#, Bi X^#, & Zhang C^#. (2023). Timp1 Deletion Induces Anxiety-like Behavior in Mice. Neuroscience bulletin. 2023 Dec 19. doi: 10.1007/s12264-023-01163-1

12. Liu M*, An Z*, Xu J*, Deng X, Xiao Y, A R, Zhan Y, Yang C, Li P^#, Fan Y^#. (2024). Netrin1-carrying magnetic microspheres with magnetic field activate neurotrophin factors to guide neuronal outgrowth in vitro and in vivo. Chemical Engineering Journal.

13. Ren P, Yang C, Xing R, Yan X^#. (2024). A tough bioadhesive based on co-assembly of polypeptide and polysaccharide for adhesion of soft tissues. Colloid Surface A.