杨肖，副教授，硕士生导师、博士生导师。2016年1月获北航工学博士学位，2016年6月入职北航生物与医学工程学院。主讲4门研究生课程、1门本科生课程。研究方向为航天生物医学工程、空间生命科学、生物力学与力学生物学。近年来主要针对空间微重力环境下骨质疏松机制开展动物组织层面和细胞层面的实验研究，研究模拟微重力效应下骨细胞对力学刺激的生物学响应，以及晚期糖基化终末产物在失重性骨丢失机制中的作用，发表SCI论文20余篇，会议论文20余篇。入选第三届中国科学青年人才托举工程，主持国家自然科学基金青年基金，参与多项省国家级项目，北航蓝天新秀、北航青年拔尖人才。中国空间科学学会理事会空间生命专委会秘书，Bone、IJMS、Medical Engineering & Physics、Life等期刊审稿人，Polymer专栏编辑。

       在本科导师制中担任本科学生导师，指导本科生进行基础科研研究。曾指导5名本科生获得2019年全国大学生挑战杯特等奖、北京航空航天大学第29届“冯如杯”生命科学类一等奖。多次指导本科生获得国家大学生创新创业训练计划资助、校级大学生创新计划资助。

代表性期刊论文：

1. Cong-Jin Liu, Xiao Yang*, Shou-Hui Wang, Xin-Tong Wu, Yan Mao, Jing-Wen Shi, Yu-Bo Fan, Lian-Wen Sun*. Preventing Disused Bone Loss Through Inhibition of Advanced Glycation End Products. International Journal of Molecular Sciences, 2023, 24(5):4953.

2. Cong-Jin Liu, Xiao Yang*, Yan Mao, Xiao-Xue Zhang, Xin-Tong Wu, Shou-Hui Wang, Yu-Bo Fan, Lian-Wen Sun*. The alteration of advanced glycation end products and its potential role on bone loss under microgravity. Acta Astronautica, 2023, 206:114-122.

3. Li-Jin Liu, Yu-Bo Fan, Shou-Hui Wang, Xin-Tong Wu, Xiao Yang*, Lian-Wen Sun*. Enhanced osteogenic potential of periosteal stem cells maintained cortical bone relatively stable under microgravity. Acta Astronautica, 2023, 205: 163-171.

4. Li-Jin Liu, Yu-Bo Fan, Xin-Tong Wu, Xiao Yang*, Lian-Wen Sun*. Comparison of stem cell characteristics between perichondral-derived stem cells and periosteal stem cells in postnatal rats. Medicine in Novel Technology and Devices, 2023, 18: 100238.

5. Li-Jin Liu, Shuang Li, Xin-Tong Wu, Xiao Yang*, Lian-Wen Sun*. Contribution of endoplasmic reticulum stress response to the mechanosensitivity alteration in osteocytes under simulated microgravity. Acta Astronautica, 2022, 191: 522-527.

6.  Zhuang Han, Lian-Wen Sun, Xin-Tong Wu, Xiao Yang*, Yu-Bo Fan*. Nonlinear dynamics of membrane skeleton in osteocyte. Computer Methods in Biomechanics and Biomedical Engineering, 2022: 249-260.

7. Yu-Hao Tong, Xiao Yang, Xin-Tong Wu, Shou-Hui Wang, Li-Jin Liu, Lian-Wen Sun*, Yu-Bo Fan*. The effect of periodic stretching on countering bone loss in hindlimb unloading rat. Acta Astronautica, 2022, 190: 202-207.

8. Xin-Tong Wu, Xiao Yang, Ran Tian, Ying-Hui Li, Cun-Yan Wang, Yu-Bo Fan*, Lian-Wen Sun*. Cells respond to space microgravity through cytoskeleton reorganization. FASEB J, 2022, 36(2):e22114.

9. Xiao Yang, Cong-Jin Liu, Zhen-Zhen Wang, Dong Ding, Jing-Wen Shi, Xin-Tong Wu, Lian-wen Sun*, Yu-bo Fan*. Effects of advanced glycation end products on osteocytes mechanosensitivity. Biochemical and Biophysical Research Communications, 2021, 568:151-157.

10. Shou-Hui Wang, Xiao Yang, Dong Ding, Xin-Tong Wu, Zhuang Han, Lian-Wen Sun*, Yu-Bo Fan*. The changes of bone vessels and their role in bone loss in tail-suspended rats. Acta Astronautica, 2021, 189: 368-378.

11. Jun-Ling Wang, Yong-Bo Zhang*, Xiao Yang*, and Xiao-Bing Ma. Stress effect on 3D culturing of MC3T3-E1 cells on microporous bovine bone slices. Nanotechnology Reviews, 2020, 9(1):1315-1325.

12. Dong Ding, Xiao Yang, Hui-Qin Luan, Xin-Tong Wu, Cai He, Lian-Wen Sun, Yu-Bo Fan. Pharmacological Regulation of Primary Cilium Formation Affects the Mechanosensitivity of Osteocytes. Calcified Tissue International, 2020: 1–11.

13.  Dong Ding, Xiao Yang, Hui-Qin Luan, Xin-Tong Wu, Lian-Wen Sun*, Yu-Bo Fan*. The microgravity induces the ciliary shortening and an increased ratio of anterograde/retrograde intraflagellar transport of osteocytes. Biochemical and Biophysical Research Communications, 2020, 530: 167–172.

14.  Shou-Hui Wang, Xiao Yang, Min Wang, Yun-Fei Huang, Dieter Blottner, Lian-Wen Sun*, Yu-Bo Fan*. The role of body fluid shifts on hindlimb bone loss in tail suspended rats using a novel body fluid alteration device. Acta Astronautica, 2019, 159: 1-7.

15. Xiao Yang, Lian-Wen Sun*, Cheng-Fei Du, Xin-Tong Wu, Yu-Bo Fan*. Finite element analysis of osteocytes mechanosensitivity under simulated microgravity. Microgravity Science and Technology, 2018, 30: 469–481.  

16. Xiao Yang, Ahmed Jenan Mostafa, Mark Appleford, Lian-Wen Sun*, Xiaodu Wang*. Bone formation is affected by matrix advanced glycation end products (AGEs) in vivo. Calcified tissue international, 2016, 99(4): 373–383.

专著（Book）：

1. Xiao Yang, Lian-Wen Sun, Xiao-Du Wang*. A Closer Look at Glycation: A Potential Hotspot for Age-Related Complications and Diseases (Chapter 5: Effects of Advanced Glycation End Products (Ages) on Bone Biomechanics and Remodeling). Nova Science Publishers. 2021.3.4. ISBN: 978-1-53619-176-9

2. 孙联文，杨肖，吴欣童。细胞力学及力学生物学（译著，原著 Introduction to cell mechanics and mechanobiology.）科学出版社。2023. 2. ISBN: 978-7-03-074583-5.

发明专利：

• 一种单轴旋转在线剪切体外细胞培养装置. 樊瑜波，杨肖，孙联文，贡向辉. ZL201110060145.7。

• 一种中空传动轴内嵌液路旋转接头与中空传动轴连接件. 杨肖，李双，何源，孙联文. ZL201911079044.7。

• 一种双注射泵不间断供液系统. 孙联文，何源，杨肖，田昊。ZL201911059398.5。

• [1]. 2009.9 -- 2016.1

  北京航空航天大学       生物医学工程       博士研究生毕业       博士学位

• [2]. 2006.9 -- 2008.7

  北京航空航天大学       外国语言文学       大学本科毕业       学士学位

• [3]. 2004.9 -- 2008.7

  北京航空航天大学       航空宇航科学与技术       大学本科毕业       学士学位

• [1]. 2023.7 -- 至今

  北京航空航天大学      生物与医学工程学院      党支部副书记      副教授      在职

• [2]. 2016.6 -- 2023.7

  北京航空航天大学      生物与医学工程学院      讲师      在职

[1]. 2019.1 -- 2023.12

中国空间科学学会空间生命专业委员会秘书

• [1] 航空航天生物医学工程
• [2] 空间生命科学
• [3] 生物力学与力学生物学