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影响因子：7.7
DOI码：10.1002/cssc.202500949
发表刊物：CHEMSUSCHEM
摘要：Direct carbonylation of the C(sp3)Cl bond remains a challenging transformation in the chemical industry. The usual use of precious metals, the high cost of ligands, and the lack of recyclability of catalysts make their industrial application on a large scale impossible. A ligand-free cobalt-based catalyst for the alkoxycarbonylation of chloroacetates to dialkyl malonates, which are important industrial intermediates, is reported here. This catalyst uses an extremely inexpensive precursor, CoCO3, with a very low catalyst loading (0.5 mol%) to achieve product yields of up to 99% with nearly 100% chemoselectivity. Solvents and previously essential phase transfer agents are not needed. Most importantly, the catalyst can be easily recycled without losing its activity and selectivity. Over 95% product yield is achieved even after 8 recycles. The feasibility of this system is demonstrated through 14 examples of the alkoxycarbonylation reaction. Fourier transform infrared spectroscopy investigations identified the active cobalt species as [Co(CO)4]−. As the first recyclable cobalt-based catalyst, this ligand-free system has great potential for large-scale industrial transfer.
合写作者：Wenyu Wang, Zhusong Cao, Yuya Hu, Rui Sang,* Qingshan Kong, Qicai Xue, and Baoxin Zhang*
论文类型：期刊论文
通讯作者：Rui Sang；Baoxin Zhang
文献类型：期刊
卷号：18
期号：17
是否译文：否
发表时间：2025-09-01
收录刊物：SCI
发布期刊链接：http://doi.org/10.1002/cssc.202500949