Impact Factor:16.4

DOI number:10.1002/anie.201701950

Journal:Angewandte Chemie International Edition

Abstract:A general palladium-catalyzed synthesis of linear esters directly from sec-and tert-alcohols is described. Compared to the classic Koch-Haaf reaction, which leads to branched products, this new transformation gives the corresponding linear esters in high yields and selectivity. Key for this protocol is the use of an advanced palladium catalyst system with L2 (pytbpx) as the ligand. A variety of aliphatic and benzylic alcohols can be directly used and the catalyst efficiency for the benchmark reaction is outstanding (turnover number up to 89 000).

Co-author:Jie Liu；Rauf Razzaq；Robert Frank；Ralf Jackstell；Matthias Beller*；

First Author:Kaiwu Dong；Rui Sang

Indexed by:Journal paper

Correspondence Author:Matthias Beller*；

Document Type:J

Volume:56

Issue:22

Page Number:6203 - 6207

Translation or Not:no

Date of Publication:2017-05-22

Included Journals:SCI

Links to published journals:https://onlinelibrary.wiley.com/doi/10.1002/anie.201701950