Impact Factor:4.3

DOI number:10.1002/adsc.201400614

Journal:ADVANCED SYNTHESIS & CATALYSIS

Abstract:Hydroquinine anthraquinone-1,4-diyl diether [(DHQ)(2)AQN]-catalyzed unprecedented asymmetric domino annulation reactions of acylidenoxindoles/isatins, acylidenoxindoles and allenoates are disclosed in this communication, providing a facile access to hexahydrofuro[2,3-b]furans containing four contiguous chiral centers in good to excellent yields along with good to excellent ee values and moderate to good dr values. Based on theoretical investigations, a concerted [3+2] ring-closure process was proposed, in which steric hindrance and pi-pi stacking interaction between catalyst and substrate subtly co-control the diastereoselectivity of the reaction.

Co-author:Zhao, Yun-Zhou；Sang, Rui；Wei, Yin*； Shi, Min*；

First Author:Yang, Hai-Bin

Indexed by:Journal paper

Correspondence Author:Wei, Yin*； Shi, Min*；

Document Type:J

Volume:356

Issue:18

Page Number:3799 - 3808

Translation or Not:no

Date of Publication:2014-12-15

Included Journals:SCI

Links to published journals:https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/adsc.201400614