Disease Mechanism Analysis and Precision Diagnosis and Treatment Modeling Based on Multi-dimensional Omics Features

Based on multi-dimensional omics systems including genomics, transcriptomics and metabolomics, this direction focuses on the molecular mechanism analysis and precise diagnosis and treatment modeling of major diseases. It establishes standardized pipelines for multi-omics data cleaning, feature screening and enrichment analysis, and deeply excavates disease-specific molecular biomarkers and core pathogenic regulatory pathways. This research addresses the defects of one-sided mechanism interpretation and inaccurate clinical prediction caused by single-omics analysis, and constructs models for disease typing, prognostic evaluation and drug efficacy prediction, providing solid theoretical and technical support for disease mechanism research and individualized precision medicine.