个人简介

王晓飞，男，北京航空航天大学教授，博士生导师，医工百人。分别于2008年、2011年和2014年毕业于中南大学、大连理工大学和新南威尔士大学，2015至2018年在新加坡国立大学从事眼科研究。主要从事与眼、视神经和脑相关疾病的医工交叉研究，目前的研究覆盖了整个眼球和前段视路（视神经）和视交叉。在眼科基础研究顶级期刊Investigative Ophthalmology & Visual Science, 柳叶刀子刊The Lancet Regional Health - Western Pacific和生物力学重要期刊 Journal of Biomechanics等杂志发表论文40余篇，主持国家级人才项目、国自然（3项）、北自然（2项）等各类基金10项。揭示了眼动与青光眼和高度近视的可能关联，受到了国际上的高度关注，目前已有不少国际著名的研究组跟进了此项研究。是Progress in Retinal and Eye Research, Investigative Ophthalmology & Visual Science, Journal of Biomechanics等知名期刊的长期审稿人。任中国研究型医院学会神经眼科专业委员会常务委员、中国医促会眼科学分会委员、世界华人生物医学工程学会终身会员；中国生物医学工程学会生物力学分会会员，美国视觉与眼科研究学会会员。

博士后招聘

因发展需要，现招聘博士后若干名，欢迎有意愿共同发展的博士们加入。课题组目前已经与北航、北京同仁医院、新加坡国立大学等课题组建立了稳定的合作关系，国际交流机会多。课题组经费充足、设备齐全、氛围和谐、充分尊重申请者的科研兴趣和发展规划。希望申请者近期获得（或即将获得）生物医学工程、力学类、生物、信息、机械、材料及其它相关专业博士学位，并满足国家有关博士后的基本申请条件。招聘广告长期有效，欢迎发简历至xiaofei.wang@buaa.edu.cn

招生信息

博士生：生物力学、力学生物学、医学图像处理与人工智能方向。申请考核制，无需考试，欢迎各专业背景的研究生和本科生加入。

硕士生：生物医学工程各方向，欢迎各专业背景的本科生报考。

代表性论文和会议报告

期刊论文和著作：

 •       Han, Y., Li, Q., Liu, T., Chen, Z., Chen, X., & Wang, X*. Quantifying gender differences in orbital morphology with large MRI datasets. Medicine in Novel Technology and Devices. 2024, 24, 100332.
 •       Han, Y. X., Guo, X. X., Wang, Y. X., Jonas, J. B., Chen, X., & Wang, X*. Automated posterior scleral topography assessment for enhanced staphyloma visualization and quantification with improved maculopathy correlation. Translational Vision Science & Technology. In press.
•       Liu, T., Hung, P. T., Wang, X.*, & Girard, M. J. A*. Effect of eye globe and optic nerve morphologies on gaze-induced optic nerve head deformations. Investigative Ophthalmology & Visual Science. 2024, 65(8), 48-48.
 •       Han, Y., Wang, X.*, Xue, C. C., Jonas, J. B., & Wang, Y. X*. Lamina cribrosa configurations in highly myopic and non-highly myopic eyes: The Beijing Eye Study. Investigative Ophthalmology & Visual Science. 2024, 65(8), 28-28.
•       Chen, X., Liu, X., He, H., Guo, X., Li, S., Huang, Y., Wang, X*., & She, H*. Stem cell factor protects against chronic ischemic retinal injury by modulating the neurovascular unit. Biomedicine & Pharmacotherapy. 2024, 173, 116318.
 •       Chuangsuwanich, T., Tun, T. A., Braeu, F. A., Wang, X., Chin, Z. Y., Panda, S. K., & Girard, M. J. A. Adduction induces large optic nerve head deformations in subjects with normal-tension glaucoma. British Journal of Ophthalmology. 2024, 108(4), 522-529.
 •       Benítez, T. M., Xu, Y., Boudreau, J. D., Kow, A. W. C., Bello, F., Van Phuoc, L., & Girard, M. J. A. Harnessing the potential of large language models in medical education: Promise and pitfalls. Journal of the American Medical Informatics Association. 2024, 31(3), 776-783.
 •       Betzler, B. K., Chen, H., Cheng, C. Y., Lee, C. S., Ning, G., Song, S. J., & Lee, A. Y. Large language models and their impact in ophthalmology. The Lancet Digital Health. 2023, 5(12), e917-e924.
•       Pushpanathan, K., Lim, Z. W., Yew, S. M. E., Chen, D. Z., Lin, H. A. H. E., Goh, J. H. L., & Tan, A. H. Popular large language model chatbots’ accuracy, comprehensiveness, and self-awareness in answering ocular symptom queries. iScience. 2023, 26(11).
•       Tun, T. A., Nongpiur, M. E., Xu, B. Y., Wang, X., Tan, M., Quah, J. H. M., & Lim, H. B. Investigating the determinants of iridolenticular contact area: A novel parameter for angle closure. British Journal of Ophthalmology. In press.
•       Fan, L., Wang, J., Li, Q., Song, Z., Dong, J., Bao, F., & Wang, X*. Eye movement characteristics and visual fatigue assessment of virtual reality games with different interaction modes. Frontiers in Neuroscience. 2023, 17, 1173127.
•       Chuangsuwanich, T., Tun, T. A., Braeu, F. A., Wang, X., Chin, Z. Y., Panda, S. K., & Girard, M. J. A. Differing associations between optic nerve head strains and visual field loss in patients with normal- and high-tension glaucoma. Ophthalmology. 2023, 130(1), 99-110.
•       Wang, X., Sanders, H. M., Liu, Y., Seang, K., Tran, B. X., Atanasov, A. G., & Qiu, Y. ChatGPT: promise and challenges for deployment in low-and middle-income countries. The Lancet Regional Health–Western Pacific. 2023, 41.
•       Xue, C. C#., Wang, X.#, Han, Y. X., Zhang, Q., Zhang, C., Wang, Y. X., & Jonas, J. B. Parapapillary gamma zone associated with increased peripapillary scleral bowing: the Beijing Eye Study 2011. British Journal of Ophthalmology. 2023, 107(11), 1665-1671.
•       Tun, T. A., Nongpiur, M. E., Xu, B. Y., Wang, X., Tan, M., Quah, J. H. M., & Lim, H. B. Investigating the determinants of iridolenticular contact area: a novel parameter for angle closure. British Journal of Ophthalmology. 2023, in press.
•       Wang, K., Xia, Y., Wang, X.*, Pu, Y., Zhao, Y., Chang, P., & Pierscionek, B. K. Influence of design parameters and capsulorhexis on intraocular lens stabilities: A 3D finite element analysis. Computers in Biology and Medicine. 2023, 160.
•       Sheng, J., Li, Q., Liu, T., & Wang, X*. Cerebrospinal fluid dynamics along the optic nerve. Frontiers in Neurology. 2022, 13, 931523.
•       Dong, J., Li, Q., Wang, X.*, & Fan, Y. A review of the methods of non-invasive assessment of intracranial pressure through ocular measurement. Bioengineering. 2022, 9(7), 304.
•       Liu, T., Sheng, J., Fan, Y., & Wang, X*. Biomechanics of the optic nerve. In Biomechanics of Injury and Prevention. 2022, 129-166.
•       Wang, X., Chang, S., Grinband, J., Yannuzzi, L., Freund, K., Hoang, Q., & Girard, M. Optic nerve tortuosity and displacements during horizontal eye movements in healthy and highly myopic subjects. British Journal of Ophthalmology. 2021, published online first.
•       Tun, T. A.#, Wang, X.#, Baskaran, M., Nongpiur, M. E., Tham, Y. C., Nguyen, D. Q., Strouthidis, N. G., Aung, T., Cheng, C. Y., & Girard, M. J. A. Determinants of lamina cribrosa depth in healthy Asian eyes: The Singapore Epidemiology Eye Study. British Journal of Ophthalmology. 2021, 105, 367-373.
•       Wang, X., Neely, A., Jain, N., Jain, S., Jain, S., McIlwaine, G., Tahtali, M., & Lueck, C. Biomechanics of human optic chiasmal compression: Ex vivo experiment and finite element modelling. Medicine in Novel Technology and Devices. 2021, in press.
•       Xin, C., Wang, X., Wang, N., Wang, R., & Johnstone, M. Trabecular meshwork motion profile from pulsatile pressure transients: A new platform to simulate transitory responses in humans and nonhuman primates. Applied Science. 2021, 12(1), 11.
•       Cheong, H., Devalla, S. K., Chuangsuwanich, T., Tun, T. A., Wang, X., Aung, T., Schmetterer, L., Buist, M. L., Boote, C., Thiéry, A. H., & Girard, M. J. A. OCT-GAN: single step shadow and noise removal from optical coherence tomography images of the human optic nerve head. Biomedical Optics Express. 2021, 12(3), 1482-98.
•       Wang, X., Tun, T. A., Nongpiur, M. E., Htoon, H. M., Tham, Y. C., Strouthidis, N. G., Aung, T., Cheng, C. Y., & Girard, M. Peripapillary sclera exhibits a V-shaped configuration that is more pronounced in glaucoma eyes. British Journal of Ophthalmology. 2020, doi: 10.1136/bjophthalmol-2020-317900.
•       Fisher, L. K., Wang, X., Tun, T. A., Chung, H. W., Milea, D., & Girard, M. Gaze-evoked deformations of the optic nerve head in thyroid eye disease. British Journal of Ophthalmology. 2021.

•       Tun TA#, Wang X#, Mani Baskaran, Monisha E Nongpiur, Yih-Chung Tham, Duc Quang Nguyen,  Nicholas G Strouthidis, Tin Aung, Ching-Yu Cheng, Michaël JA Girard. Determinants of Lamina Cribrosa Depth in Healthy Asian Eyes: The Singapore Epidemiology Eye Study. British Journal of Ophthalmology. 2020, in press

•       Jin Y#, Wang X#, Irnadiastputri S, Mohan R, Aung T, Perera SA, Boote C, Jonas JB, Schmetterer L, & Girard, MJA. Effect of Changing Heart Rate on the Ocular Pulse and Dynamic Biomechanical Behavior of the Optic Nerve Head. Investigative ophthalmology & visual science. 2020, 61(4), 27

•       Chuangsuwanich T, Pham TH, Wang X, Liang LH, Schmetterer L, Boote C, Girard MJA. Morphometric, Hemodynamic and Biomechanical Factors influencing Blood Flow and Oxygen Concentration in the Human Lamina Cribrosa. Investigative ophthalmology & visual science. 2020, 61(4), 3

•       Cheng H, Devalla SK, Pham TH, Zhang L, Tun TA, Wang X, Perera SA, Aung T, Boote C, Thiery A, Michaël JA Girard. DeshadowGAN: A Deep Learning Approach to Remove Shadows from Optical Coherence Tomography Images. Translational Vision Science & Technology. 2020, 9(2), 23

•       Zhang L, Beotra MR, Baskaran M, Tun TA, Wang X, Perera SA, Strouthidis NG, Aung T, Boote C, Girard MJA. In Vivo Measurements of Prelamina and Lamina Cribrosa Biomechanical Properties in Humans. Investigative ophthalmology & visual science. 2020, 61(3), 27

•       Tun TA#, Wang X#, Mani Baskaran, Monisha E Nongpiur, Yih-Chung Tham, Shamira A Perera, Nicholas G Strouthidis, Tin Aung, Ching-Yu Cheng, Michaël JA Girard. Variation of Peripapillary Scleral Shape With Age. Investigative ophthalmology & visual science. Aug. 2019, 60 (10), 3275-328

•       Devalla SK, Subramanian G, Pham TH, Wang X, Perera S, Tun TA, Aung T, Schmetterer L, Thiéry AH, Girard MJ. A deep learning approach to denoise optical coherence tomography images of the optic nerve head. Scientific reports. 2019 Oct 8;9(1):1-3

•       Tan NY, Tham YC, Thakku SG, Wang X, Baskaran M, Tan MC, Mari JM, Strouthidis NG, Aung T, Girard MJ, Cheng CY. Changes in the Anterior Lamina Cribrosa Morphology with Glaucoma Severity. Scientific reports. 2019 Apr 29;9(1):6612.

•       Wang, X, Rumpel, H, Baskaran, M, Tun, T, Strouthidis, N, Perera, S, Lim, W, Nongpiur, ME, Lim, W, Aung, T, Milea, D, Girard, MJA. Optic Nerve Tortuosity and Globe Proptosis in Normal and Glaucoma Subjects. Journal of Glaucoma, Aug. 2019, 28 (8), 691-696

•       Tan, R.; Wang, X; Chan, Anita S. Y.; Nongpiur, Monisha E.; Boote, Craig; Perera, Shamira; Girard, Michael, Permeability of the porcine iris stroma, Experimental Eye Research, Apr. 2019, 181: 190~196

•       Jin, Y., Wang, X, Zhang, L., Jonas, J. B., Aung, T., Schmetterer, L., & Girard, M. J. Modeling the Origin of the Ocular Pulse and Its Impact on the Optic Nerve Head. 2018. Investigative ophthalmology & visual science, Aug. 2018, 59(10), 3997-4010.

•       Wang, X, Teoh, C. K. G., Chan, A. S., Thangarajoo, S., Jonas, J. B., & Girard, M. J. Biomechanical Properties of Bruch's Membrane–Choroid Complex and Their Influence on Optic Nerve Head Biomechanics. Jun. 2018. Investigative Ophthalmology & Visual Science, 59(7), 2808-2817.

•       Beotra MR, Wang X, Tun TA, Zhang L, Baskaran M, Aung T, Strouthidis NG, Girard MJA. In Vivo 3-Dimensional Lamina Cribrosa Strains in Healthy, Ocular Hypertensive and Glaucoma Eyes following Acute Intraocular Pressure Elevation. Jan. 2018. Investigative Ophthalmology & Visual Science. 59(1), 260-272

•       Wang X, Fisher LK, Milea D, Jonas JB, Girard MJA. Predictions of Optic Nerve Traction Forces and Peripapillary Tissue Stresses Following Horizontal Eye Movements. Investigative Ophthalmology & Visual Science. Apr. 2017. Vol. 58, 2044-2053

•       Wang X, Beotra MR, Zhang L, Girard MJA. In vivo Characterization of Optic Nerve Head Biomechanics for Improved Glaucoma Management. In: Roberts CJ, Dupps WJ, Downs CD, eds. Biomechanics of the Eye. Amsterdam, The Netherlands: Kugler Publications; 2018.

•       Wang X, Beotra MR, Tun TA, Baskaran M, Perera SA, Aung T, Strouthidis NG, Milea D, Girard MJA. In Vivo 3-Dimensional Strain Mapping Confirms Large Optic Nerve Head Deformations Following Horizontal Eye Movements. Investigative Ophthalmology & Visual Science. Oct. 2016. Vol.57, 5825-5833. doi:10.1167/iovs.16-20560 .

•       Wang X, Rumpel H, Lim WEH, Baskaran M, Perera SA, Nongpiur ME, Aung T, Milea D, Girard MJA. Finite Element Analysis Predicts Large Optic Nerve Head Strains During Horizontal Eye Movements. May 2016. Investigative Ophthalmology & Visual Science. Vol.57, 2452-2462. doi:10.1167/iovs.15-18986.

•       Wang X, Rumpel H, Lim WEH, Baskaran M, Perera SA, Nongpiur ME, Aung T, Milea D, Girard MJA. Author Response: Peripapillary Suprachoroidal Cavitation, Parapapillary Gamma Zone and Optic Disc Rotation due to the Biomechanics of the Optic Nerve Dura Mater. 2016. Investigative Ophthalmology & Visual Science. Aug. 2016, Vol.57, 4374-4375. doi:10.1167/iovs.16-20118

•       Wang X, Neely A, McIlwaine G and Lueck C. Biomechanics of Chiasmal Compression: Sensitivity of the Mechanical Behaviours of Nerve Fibres to Variations in Material Property and Geometry. International Journal for Computational Methods in Engineering Science & Mechanics. 2016. Vol.17(3): 165-171. doi: 10.1080/15502287.2015.1084069

•       Wang X, Neely A, McIlwaine G and Lueck C. Multi-scale analysis of optic chiasmal compression by finite element modelling. Journal of Biomechanics. 47 (10), pp. 2292-2299. doi: 10.1016/j.jbiomech.2014.04.040

•       Wang X, Neely A, McIlwaine G, Tahtali M, Lillicrap T and Lueck C. Finite element modelling of optic chiasmal compression. Journal of Neuro-Ophthalmology. 34(4): 324-30. doi: 10.1097/WNO.0000000000000145

•       Jain N, Jain S, Wang X, Neely A, Tahtali M, Jain S and Lueck C. Visualization of Nerve Fiber Orientations in the Human Optic Chiasm Using Photomicrographic Image Analysis. Investigative Ophthalmology & Visual Science. 2015, Vol.56 (11), 6734-6739. doi:10.1167/iovs.15-17443

•       Tan R, Wang X, Shamira P, Girard MJA. Numerical Stress Analysis of the Iris Tissue Induced by Pupil Expansion: Comparison of Commercial Devices. PLOS ONE. 2018. in press

•       Lillicrap T, Tahtali M, Neely A, Wang X, Bivard A, and Lueck C. A Model Based on the Pennes Bioheat Transfer Equation is Valid in Normal Brain Tissue but not Brain Tissue Suffering Focal Ischaemia. Australian Physical & Engineering Sciences in Medicine. 2017.

会议论文/摘要：

•     Wang X, Neely A, McIlwaine G and Lueck C. Biomechanics of chiasmal compression: sensitivity of the mechanical behaviours of nerve fibres to variations in material property and geometry. 11th World Congress on Computational Mechanics, 20-25 July 2014, Barcelona, Spain.

•     Wang X, Neely A, Lueck C, Tahtali M, McIlwaine G and Lillicrap T (2012) Parametric studies of optic chiasmal compression biomechanics using finite element modelling, 7th Australasian Congress on Applied Mechanics, 9-12 December 2012, Adelaide, Australia

•     Lillicrap T, Tahtali M, Neely A, Lueck C and Wang X, (2012) Finite Element Modelling of heat exchange in the stroke-affected brain during therapeutic hypothermia, 7th Australasian Congress on Applied Mechanics, ACAM 7 9-12 December 2012, Adelaide, Australia

•     Fisher, L  Wang, X; Tun, TA; Chung, HW; Milea, D; Girard, MJA. Gaze Evoked Deformations of the Optic Nerve Head in Thyroid Eye Disease. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO)  APR 28-MAY 02, 2019, Vancouver, CANADA.

•     Jin, YJ; Wang, XF; Irnadiastputri, SFR; Mohan, RE; Aung, T; Schmetterer, L; Girard, MJA. Effect of Changing Heart Rate and Body Posture on the Ocular Pulse Amplitude and Optic Nerve Head Deformations, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO)  APR 28-MAY 02, 2019, Vancouver, CANADA.

•     Tun, TA ; Wang, XF; Aung, T; Cheng, CY; Girard, MJA. Determinants of Lamina Cribrosa Depth in Asian Eyes, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO)  APR 28-MAY 02, 2019, Vancouver, CANADA.

•     Wang, XF; Hoang, QV; Chang, S; Yannuzzi, LA; Freund, KB; Milea, D; Girard, MJA. Optic nerve displacements during horizontal eye movements in healthy and high myopic subjects. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO)  APR 28-MAY 02, 2019, Vancouver, CANADA.

•     Jin, YJ; Wang, XF; Zhang, L; Jonas, JB; Aung, T; Schmetterer, L; Girard, MJA. Finite Element Modeling Predicts Neural Tissue Shear in the Neuroretinal Rim Caused by Pulsatile Blood Pressure, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO)  APR 29-MAY 03, 2018, Honolulu, HI.

•     Tun, TA; Wang, XF; Mani, B; Nongpiur, ME; Cheng, CY; Strouthidis, N; Aung, T; Girard, MJA. Effect of Age and Glaucoma on Anterior Peripapillary Sclera Shape, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO)  APR 29-MAY 03, 2018, Honolulu, HI.

•     Girard, MJA; Fisher, LK; Milea, D; Jonas, JB; Wang, XF. Predictions of Optic Nerve Traction Forces and Optic Nerve Head Tissue Stresses Following Horizontal Eye Movements, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO)  MAY 07-11, 2017, Baltimore, MD

•     Wang X, Baskaran M, Rumpel H, Perera S, Lim W, Nongpiur ME, Aung T, Milea D, Girard MJA. Finite element analysis predicts high optic nerve head strains during horizontal eye movements., Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO)  MAY 01-05, 2016, Seattle, WA.

大会报告：

•    王晓飞, 高度近视患者水平眼动中视神经的弯曲度和位移研究, 2019年中国生物材料大会, 大连，2019.8.23

•    Wang X, Fan YB. Finite Element Modelling Predicts Large Accommodation Induced Optic Nerve Head Deformations. Presented at International Conference on Biomechanics and Medical Engineering (ICBME 2019), San Diego, USA, 20 – 23 September, 2019.

•       王晓飞, 视乳头在体生物力学研究进展（邀请报告）, 第十二届全国青光眼学术会议, 贵阳, 2018.11.15-2018.11.17

•       王晓飞, 眼动导致的视乳头变形研究（优秀论文奖）, 第十二届全国生物力学大会, 西安，2018.8.20

•    Wang X, Baskaran M, Rumpel H, Perera S, Lim W, Nongpiur ME, Aung T, Milea D, Girard MJA. Finite element analysis predicts high optic nerve head strains during horizontal eye movements. Presented at Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, Seattle, USA, May 1-5 2016 （会议热门话题；2%）

•       Wang X, Neely A, Lueck C, Tahtali M, McIlwaine G and Lillicrap T (2012) Parametric studies of optic chiasmal compression biomechanics using finite element modelling, Presented at the 7th Australasian Congress on Applied Mechanics, 9-12 December 2012, Adelaide, Australia

•    Wang X, Neely A, McIlwaine G, Tahtali1 M, Lillicrap T, Lueck C. Finite Element Modelling of Optic Chiasmal Compression. Presented at the Canberra Health Annual Research Meeting, Canberra, ACT, AUSTRALIA, 20 – 23 August, 2013.

•    Wang X, Neely A, McIlwaine G and Lueck C. Biomechanics of chiasmal compression: sensitivity of the mechanical behaviours of nerve fibres to variations in material property and geometry. Presented at the 11th World Congress on Computational Mechanics; 20-25 July 2014, Barcelona, Spain.